BindingDB PrimarySearch

Found 7 hits of ic50 for drug = Adderall 20
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Transporter (Rattus norvegicus (rat))	BDBM50005246 (1-Phenylpropan-2-amin \| 1-phenyl-2-aminopropane \| ...) Show SMILES CC(N)Cc1ccccc1 Show InChI	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at NET expressed in rat hypothalamic homogenate containing synaptosomes after 5 mins by scintillation countin...				J Med Chem 19: 725-7 (1976) BindingDB Entry DOI: 10.7270/Q2FN17RB
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005246 (1-Phenylpropan-2-amin \| 1-phenyl-2-aminopropane \| ...) Show SMILES CC(N)Cc1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine uptake at dopamine transporter expressed in rat striatal homogenate after 5 mins by scintillation counting analysis				J Med Chem 19: 725-7 (1976) BindingDB Entry DOI: 10.7270/Q2FN17RB
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (MOUSE)	BDBM50005246 (1-Phenylpropan-2-amin \| 1-phenyl-2-aminopropane \| ...) Show SMILES CC(N)Cc1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of noradrenaline transporter in NMRI albino mouse brain assessed as [3H]NA accumulation in hypothalamus after 5 mins				J Med Chem 21: 78-82 (1978) BindingDB Entry DOI: 10.7270/Q2P270P4
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2A5 (Mus musculus)	BDBM50005246 (1-Phenylpropan-2-amin \| 1-phenyl-2-aminopropane \| ...) Show SMILES CC(N)Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Inhibitory concentration against mouse cytochrome P450 2A5				J Med Chem 48: 440-9 (2005) Article DOI: 10.1021/jm049536b BindingDB Entry DOI: 10.7270/Q20C4WJV
University of Kuopio Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2A6 (Homo sapiens (Human))	BDBM50005246 (1-Phenylpropan-2-amin \| 1-phenyl-2-aminopropane \| ...) Show SMILES CC(N)Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Inhibitory concentration against human cytochrome P450 2A6				J Med Chem 48: 440-9 (2005) Article DOI: 10.1021/jm049536b BindingDB Entry DOI: 10.7270/Q20C4WJV
University of Kuopio Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 3 (Rattus norvegicus)	BDBM50005246 (1-Phenylpropan-2-amin \| 1-phenyl-2-aminopropane \| ...) Show SMILES CC(N)Cc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Medical College of Georgia Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 1 uM) in OCT3-expressing HRPE cells				J Biol Chem 273: 32776-86 (1998) Article DOI: 10.1074/jbc.273.49.32776 BindingDB Entry DOI: 10.7270/Q2ZK5KHT
Medical College of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (MOUSE)	BDBM50005246 (1-Phenylpropan-2-amin \| 1-phenyl-2-aminopropane \| ...) Show SMILES CC(N)Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 5-HT transporter in NMRI albino mouse brain assessed as [3H]5-HT accumulation in hypothalamus after 5 mins				J Med Chem 21: 78-82 (1978) BindingDB Entry DOI: 10.7270/Q2P270P4
TBA Curated by ChEMBL					More data for this Ligand-Target Pair